Article ID Journal Published Year Pages File Type
2006429 Peptides 2011 6 Pages PDF
Abstract
► Human cathelicidin LL37 and its fragments LL13-37 and LL17-32 inhibited HIV-1 reverse transcriptase dose-dependently with an IC50 value of 15 μM, 7 μM, and 70 μM, respectively. ► Human cathelicidin LL37 and its fragments LL13-37 and LL17-32 inhibited HIV-1 protease with a weak potency. ► The peptides did not exert toxicity on human peripheral blood mononuclear cells.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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