Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006429 | Peptides | 2011 | 6 Pages |
Abstract
⺠Human cathelicidin LL37 and its fragments LL13-37 and LL17-32 inhibited HIV-1 reverse transcriptase dose-dependently with an IC50 value of 15 μM, 7 μM, and 70 μM, respectively. ⺠Human cathelicidin LL37 and its fragments LL13-37 and LL17-32 inhibited HIV-1 protease with a weak potency. ⺠The peptides did not exert toxicity on human peripheral blood mononuclear cells.
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Authors
Jack Ho Wong, Anna Legowska, Krzysztof Rolka, Tzi Bun Ng, Mamie Hui, Chi Hin Cho, Wendy Wai Ling Lam, Shannon Wing Ngor Au, Oscar Wangang. Gu, David Chi Cheong Wan,