Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006506 | Peptides | 2011 | 7 Pages |
Abstract
â¶ The high glucose induced increase in expression of NO, NOS and ET-1 were significantly attenuated by pretreatment with endomorphin1/endomorphin2. â¶ Naloxone, do not influence the mRNA eNOS expression when it is administrated alone; but it could significantly antagonize the effects induced by EM1/EM2. â¶ These findings have revealed the molecular mechanism of endomorphins on protecting HUVECs from harmful conditions induced by high glucose.
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Authors
Jing Liu, Suhong Wei, Limin Tian, Liping Yan, Qian Guo, Xiaoqin Ma,