Article ID Journal Published Year Pages File Type
2006506 Peptides 2011 7 Pages PDF
Abstract
▶ The high glucose induced increase in expression of NO, NOS and ET-1 were significantly attenuated by pretreatment with endomorphin1/endomorphin2. ▶ Naloxone, do not influence the mRNA eNOS expression when it is administrated alone; but it could significantly antagonize the effects induced by EM1/EM2. ▶ These findings have revealed the molecular mechanism of endomorphins on protecting HUVECs from harmful conditions induced by high glucose.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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