Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006599 | Peptides | 2011 | 8 Pages |
Abstract
â¶ Perfusion of angiotensin II into isolated beating atria decreased the ANP secretion. â¶ The suppression of ANP secretion by angiotensin II was more prominent in high-stretched beating atria. â¶ Angiotensin II-induced suppression of ANP secretion was blocked by AT1 receptor blocker. â¶ Losartan augmented stretch-induced ANP secretion. â¶ In renal hypertensive atria, the responses of ANP secretion to angiotensin II and losartan were accentuated because of upregulation of AT1 receptor.
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Authors
Young-Bin Oh, Shan Gao, Amin Shah, Jong Hun Kim, Woo Hyun Park, Suhn Hee Kim,