Article ID Journal Published Year Pages File Type
2006684 Peptides 2010 7 Pages PDF
Abstract
▶ Saporin, when conjugated to NPY (NPY-SAP), kills cells expression NPY receptors. ▶ Injecting NPY-SAP into the central amygdala (CeA) reduces local Y1 receptor levels. ▶ Injecting NPY-SAP into the CeA increases anxiety-like behavior. ▶ NPY-SAP may be a useful tool to study the central NPY circuitry modulating anxiety.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, ,