Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006684 | Peptides | 2010 | 7 Pages |
Abstract
ⶠSaporin, when conjugated to NPY (NPY-SAP), kills cells expression NPY receptors. ⶠInjecting NPY-SAP into the central amygdala (CeA) reduces local Y1 receptor levels. ⶠInjecting NPY-SAP into the CeA increases anxiety-like behavior. ⶠNPY-SAP may be a useful tool to study the central NPY circuitry modulating anxiety.
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Authors
Angela M. Lyons, Todd E. Thiele,