Article ID Journal Published Year Pages File Type
2006702 Peptides 2010 4 Pages PDF
Abstract
▶ Both MC3R and MC4R knockout mice show partial anorectic responses to MTII. ▶ Fos induced by MTII reduced in PVN of MC3R knockout and in AP of MC4R knockout. ▶ Mice with knockout of both receptors show neither anorexia nor induced Fos. ▶ Suggests dissociation of brain region and MC receptor subtype in feeding behavior.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Effect of MTII on food intake and brain c-Fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice
Authors
, , , , ,