Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006798 | Peptides | 2010 | 7 Pages |
Abstract
â¶ Post-natal complex stress induce type-2 diabetes signs in adult male mice. â¶ Some signs depend on the endogenous opioid system upset and are prevented by naloxone. â¶ Other diabetes signs depend on HPA hormones upset. â¶ All diabetes signs are prevented by antisense oligonucleotide versus pro-opiomelanocortin. â¶ Different diabetes signs in our model are modulated through different pathogenetic mechanisms.
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Authors
Stefano Loizzo, Gabriele Campana, Stefano Vella, Andrea Fortuna, Gabriella Galietta, Irene Guarino, Loredana Costa, Anna Capasso, Paolo Renzi, Giovanni V. Frajese, Flavia Franconi, Alberto Loizzo, Santi Spampinato,