Article ID Journal Published Year Pages File Type
2006832 Peptides 2010 7 Pages PDF
Abstract
▶ Perfusion of hyposmolar solution into the atria increased the ANP secretion. ▶ Ang-(1-7) decreased the hyposmolarity-induced ANP secretion via Na+-K+ pump. ▶ In DM atria, the response of ANP secretion to hyposmolar solution was robustly accentuated. ▶ Ang-(1-7) had no effect on hyposmolarity-induced ANP secretion in DM atria partly because of potent inhibition of Na+-K+ pump.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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