| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2008801 | Peptides | 2005 | 4 Pages |
Abstract
In this study, we investigated the immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in guinea pig and rat isolated pancreatic acini. In dispersed acinar cells from guinea pig, immunofluorescence staining detected similar densities of NK-1 and NK-3 receptors; conversely, rat acinar cells expressed NK-1 receptors more strongly than NK-3 receptors. In line with previous functional studies, these immunocytochemical findings suggest that guinea pig NK-1 and NK-3 receptors and rat NK-1 receptors alone play a direct stimulatory role in the basal pancreatic acinar amylase release.
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Authors
Maria Broccardo, M. Teresa Ciotti, Giorgio Linari, Simona Agostini, Carla Petrella, Giusy Amadoro, Cinzia Severini, Giovanna Improta,