Article ID Journal Published Year Pages File Type
2013084 Pharmacology Biochemistry and Behavior 2012 8 Pages PDF
Abstract
► We describe the anti-stress effect of the CRF1 antagonist SSR125543. ► Results showed that this action does not necessarily involve HPA axis blockade. ► This suggests that extra-hypothalamic CRF1-Rs may play a role in these effects.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
The CRF1 receptor antagonist SSR125543 attenuates long-term cognitive deficit induced by acute inescapable stress in mice, independently from the hypothalamic pituitary adrenal axis
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