Article ID Journal Published Year Pages File Type
2013087 Pharmacology Biochemistry and Behavior 2012 8 Pages PDF
Abstract
► Animal model to assess the relationship between adolescent and adult drug abuse. ► Discriminative stimuli of delta-9-tetrahydrocannabinol (THC) were assessed. ► Ovarian hormones (OVX) modified the effects of chronic THC in adolescent female rats. ► Adolescent OVX and chronic THC affected the molecular protein CREB, but not ERK. ► OVX and chronic THC differentially affected the striatum and hippocampus.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Ovarian hormones and chronic administration during adolescence modify the discriminative stimulus effects of delta-9-tetrahydrocannabinol (Δ9-THC) in adult female rats
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