Article ID Journal Published Year Pages File Type
2013210 Pharmacology Biochemistry and Behavior 2011 26 Pages PDF
Abstract
► Cognition enhancement is a major challenge for drug discovery in schizophrenia (SCZ). ► Cognitive domains impaired in SCZ can be measured in animal models. ► Pharmacological models do not dissociate among different cognitive domains. ► These models fail to distinguish between cognitive enhancers and antipsychotics. ► There is a need to develop models of antipsychotic-resistant cognitive deficits.
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