Article ID Journal Published Year Pages File Type
2013410 Pharmacology Biochemistry and Behavior 2011 8 Pages PDF
Abstract
► Cocaine has both positive (rewarding) and negative (anxiogenic) properties. ► Brain serotonergic (5-HT) systems have been implicated in the modulation of anxiety. ► Inactivation of the dorsal raphé nucleus reduced the anxiogenic response to cocaine. ► 5-HT is involved in the anxiogenic state produced by cocaine.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Inactivation of the dorsal raphé nucleus reduces the anxiogenic response of rats running an alley for intravenous cocaine
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