Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2013486 | Pharmacology Biochemistry and Behavior | 2010 | 9 Pages |
Abstract
Thus, the mania-like exploratory profile of DAT KD mice is reduced in a familiar environment, partially reinstated with novelty, but is fully restored when administered a stimulant that is ineffective in wildtype mice. These mice may provide a model of BD from mania to euthymia and back again with stimulant treatment. Acute blockade of the DAT by GBR 12909 however, may provide a consistent model for BD mania.
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Authors
Jared W. Young, Andrew K.L. Goey, Arpi Minassian, William Perry, Martin P. Paulus, Mark A. Geyer,