| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2013566 | Pharmacology Biochemistry and Behavior | 2009 | 6 Pages |
Abstract
The present study shows that both stressful and stress-free drug injection shortly before a stressor results in reproducible attenuation of the SIH response in rats. In rats, a short injection-stressor interval can therefore be applied using the SIH model, enabling the study of putative anxiolytic drugs with short half-lives.
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Authors
Christiaan H. Vinkers, Noëlle M. de Jong, Cor J. Kalkman, Koen G.C. Westphal, Ruud van Oorschot, Berend Olivier, S. Mechiel Korte, Lucianne Groenink,