Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2014336 | Pharmacology Biochemistry and Behavior | 2007 | 10 Pages |
Abstract
PPI is disrupted by AMPH administered sc or into the NACc in SD but not LE rats. Reduced PPI after ic vehicle infusion in LE vs. SD rats may reflect greater PPI-reducing effects of restraint stress in LE rats. The differential impact of restraint on PPI in SD vs. LE rats complicates the interpretation of strain differences in the effects of ic manipulations, but may provide an avenue for investigating the basis for differences in vulnerability to the gating-disruptive effects of stress. Supported by MH68366, MH01436.
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Authors
Neal R. Swerdlow, Jody M. Shoemaker, Michele J. Bongiovanni, Alaina C. Neary, Laura S. Tochen, Richard L. Saint Marie,