| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 20160 | Journal of Bioscience and Bioengineering | 2015 | 4 Pages |
Abstract
We constructed a DNA damage-responsive transgene expression system mediated by the p53 promoter. We incorporated a transactivation system to generate transcriptional amplification via a positive feedback loop. Higher levels of DNA damage-responsive transgene expression were observed when transactivation was active.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Akihiko Ono, Akira Ito, Taiga Suzuki, Masaki Yamaguchi, Yoshinori Kawabe, Masamichi Kamihira,