| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2019461 | Prostaglandins & Other Lipid Mediators | 2016 | 5 Pages |
Abstract
In summary, when analysed by the 32P-postlabelling method all four racemic EETs formed multiple DNA adducts after activation by acidic pH, only ±11,12-EET produced DNA adducts in aqueous solution at neutral pH. Therefore, we conclude from our in vitro studies that EETs might be endogenous genotoxic compounds.
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Authors
Dorothee J. Funk, Bernd L. Sorg, Klaus Kopka, Heinz H. Schmeiser,