| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2019640 | Prostaglandins & Other Lipid Mediators | 2012 | 7 Pages |
Abstract
⺠We conducted a systematic survey of naturally occurring HPGDS enzyme variants. ⺠A high stability Val187Ile variant occurs in 8% of African Americans and 2% of Caucasians. ⺠Val187Ile does not protect against colon cancer. ⺠Other methods will be needed to establish a role for HPGDS in development of human intestinal tumors, as shown by mouse model data.
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Authors
Brigette L. Tippin, A. Joan Levine, Alicia M. Materi, Wen-Liang Song, Temitope O. Keku, Julie E. Goodman, Leah B. Sansbury, Sudipto Das, Aihua Dai, Alan M. Kwong, Amy M. Lin, John M. Lin, Jae Man Park, Ruth E. Patterson, Rowan T. Chlebowski,