Article ID Journal Published Year Pages File Type
2019709 Prostaglandins & Other Lipid Mediators 2011 7 Pages PDF
Abstract
► N-docsahexanoylethanolamide (DEA) is a potent synaptogenic factor, and thus termed synapamide. ► Docosahexaenoic acid (DHA) is converted to DEA by fetal mouse hippocampal neurons. ► DEA is present in the mouse hippocampus. ► DEA stimulates neurite growth, synaptogenesis and glutamatergic synaptic activities. ► DEA increases synapsin and glutamate receptor subunit expression in the hippocampal neurons.
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