| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2019761 | Prostaglandins & Other Lipid Mediators | 2011 | 8 Pages |
Abstract
⺠Lysophosphatidic acid (LPA) is assuming a growing significance in human osteoblast biology. ⺠Importantly LPA is known to co-operate with calcitriol, an essential factor in bone development. ⺠Whether LPA and calcitriol might influence osteoblast formation from their mesenchymal progenitors is unknown. ⺠Herein we present evidence that LPA and calcitriol promote human osteoblast development. ⺠Our findings extend the potential of LPA as an adjunct for bone repair and regeneration.
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Authors
J.P. Mansell, M. Nowghani, M. Pabbruwe, I.C. Paterson, A.J. Smith, A.W. Blom,