Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2019768 | Prostaglandins & Other Lipid Mediators | 2012 | 6 Pages |
Abstract
⺠COX-2-silencing reduces the nuclear accumulation of LEF-1 and the effect is partially restored by addition of PGE2. ⺠PGE2 is not required for the nuclear accumulation of β-catenin. ⺠Noncanonical activation of the Wnt pathway in cancer cells may be context-specific.
Keywords
COXGSKWntFAPAPCTCF12-O-tetradecanoylphorbol-13-acetatePGEshRNAtPAFBSPBSshort hairpin RNAFAP, Familial Adenomatous Polyposisadenomatous polyposis colicyclooxygenaseinterleukinfetal bovine serumT-cell factorlymphoid enhancer factorphosphate buffer salineLefprostaglandincasein kinaseglycogen synthase kinase
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Authors
Ioannis Stasinopoulos, Tiffany Greenwood, Kristine Glunde, Zaver M. Bhujwalla,