Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2019773 | Prostaglandins & Other Lipid Mediators | 2012 | 6 Pages |
Abstract
⺠The effect of TNF on COX-2 expression was determined in the renal OM. ⺠An elevation in urinary TNF was seen in WT mice given a vitamin D analog (DHT). ⺠An increase in urinary PGE2 was observed in WT mice treated with DHT. ⺠COX-2 expression in the OM was elevated in WT but not TNFâ/â mice given DHT. ⺠We demonstrated that during hypercalcemia COX-2 expression in the renal OM is TNF-dependent.
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Authors
Sailaja Battula, Shoujin Hao, Paulina L. Pedraza, Charles T. Stier, Nicholas R. Ferreri,