| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2019850 | Prostaglandins & Other Lipid Mediators | 2012 | 9 Pages |
Abstract
⺠Epoxyeicosatrienoic acids (EETs) are renal vasodilator and natriuretic eicosanoids. ⺠Adenosine-activated renovascular dilatation is mediated via A2A receptor (R) which is linked to increasing EET synthesis. ⺠The A2A R-EET pathway is upregulated in normotensive rats and contributes to the adaptive response to high salt intake. ⺠Failure to upregulate the A2A R-EET pathway may contribute to the development of salt-sensitive hypertension.
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Authors
Mairéad A. Carroll,