Article ID Journal Published Year Pages File Type
2020680 Protein Expression and Purification 2012 8 Pages PDF
Abstract
► We characterized the soluble extracellular domains of human SIRPα and CD47. ► These fusion proteins could promote phagocytosis of tumor cells by macrophages. ► The hSIRPext binds to tumor cells via the specific interaction with CD47.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Soluble extracellular domains of human SIRPα and CD47 expressed in Escherichia coli enhances the phagocytosis of leukemia cells by macrophages in vitro
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