Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
20226 | Journal of Bioscience and Bioengineering | 2015 | 4 Pages |
Abstract
Embryonic stem cell (ESC) pluripotency is maintained by core transcription factors (TFs). Although the expression of these TFs is well documented, their expression dynamics is poorly evaluated. Here, we visualized the dynamics of Nanog and Oct3/4 expression in ESC using fluorescent reporters and found that expression of these TFs change dramatically during culture.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Brit G. David, Kazuko Okamoto, Taishi Kakizuka, Taro Ichimura, Tomonobu M. Watanabe, Hideaki Fujita,