Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2023641 | Seminars in Cancer Biology | 2014 | 10 Pages |
Abstract
Several reports suggest that multiple factors need to be considered in order to improve exosomal immunogenicity for cancer immunotherapy. These include antigen-loading strategies, exosome composition and exosomal trafficking in vivo. Hence, a better understanding of how to engineer and deliver exosomes to specific cells is crucial to generate strong immune responses and to improve the immunotherapeutic potential of exosomes.
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Authors
Ulf Gehrmann, Tanja I. Näslund, Stefanie Hiltbrunner, Pia Larssen, Susanne Gabrielsson,