Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2027989 | Steroids | 2012 | 5 Pages |
Abstract
⺠3â²-Methoxy-E-diethylstilbestrol (2) is a metabolite of diethylstilbestrol. ⺠2 and its analogues (8 and 11) were synthesized as tumor angiogenesis inhibitors. ⺠The configuration was determined via the X-ray crystal diffraction of its derivative. ⺠2, 8 and 11 showed potential anti-proliferation activities at a close level. ⺠The exposed hydroxyl-groups in the structures are required for their bioactivities.
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Authors
Qian Liu, Weiwei Jin, Yan Zhu, Jieyun Zhou, Min Lu, Qian Zhang,