Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028012 | Steroids | 2013 | 5 Pages |
Abstract
•A concise synthesis of C17-OH-north unit of ritterazine G.•Discovery of a novel method for steroidal E-ring opening.•A highly efficient, stereoselective introduction of the C17-OH.
The C17-OH-north unit of ritterazine G was prepared in 13 steps from hecogenin acetate. This synthesis features a highly efficient and stereoselective introduction of the C17-OH via E-ring cleavage/F-ring formation, D-ring oxidation, and F-ring cleavage/E-ring formation.
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Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Young Cheun, Yi Kou, Begoña Stevenson, Hee-Kwon Kim, Myong Chul Koag, Seongmin Lee,