Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028048 | Steroids | 2012 | 9 Pages |
Abstract
⺠16-Imidazolyl substituted steroidal derivatives have been synthesized and studied. ⺠The compounds 6 and 7 exhibited aromatase inhibition better than exemestane. ⺠The bis-quaternary steroids 13 and 14 displayed potent NMJ blocking activity. ⺠Compound 13 displayed high anticholinesterase activity with Ki = 25 nM.
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Authors
Ranju Bansal, Sheetal Guleria, Sridhar Thota, Subhash L. Bodhankar, Moreshwar R. Patwardhan, Christina Zimmer, Rolf W. Hartmann, Alan L. Harvey,