| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2028049 | Steroids | 2012 | 5 Pages |
Abstract
A novel functionalized steroidal BINOL scaffold is produced via a remarkable sequence of dehydrogenation, chlorination and atroposelective phenolic coupling steps. Its formation is straightforwardly obtained in a one-step synthesis under solid state conditions and in the absence of chiral additives.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Estradiol direct functionalization. ► One-step synthesis under solid state conditions. ► Atropostereoselective phenolic coupling.
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Authors
Liliana Lista, Alessandro Pezzella, Paola Manini, Alessandra Napolitano, Marco d’Ischia,