Influences of Î²-HCG administration on carbon isotope ratios of endogenous urinary steroids

Article ID	Journal	Published Year	Pages	File Type
2028051	Steroids	2012	11 Pages	PDF

Abstract

âº Administration of Î²-HCG has significant influence on 13C/12C ratios of urinary steroids. âº The found difference is too small to identify illicit Î²-HCG administration by athletes. âº 13C/12C ratios of testicular steroids differ from steroids produced in the adrenal gland. âº Influence is found in both main excretion forms, glucuronidated and sulfated steroids. âº Steroid concentration ratios were not found advantageous to identify Î²-HCG administration.

Keywords

ERC EPIA ETIO TESTO Etiocholanolone DHEA tBME Pregnanediol EPIT DHT CIR WADA CYP17 dehydroepiandrosterone CHOL IRMS GC/C/IRMS Androsterone World Anti-Doping Agency Acetate Endogenous steroids standard deviation Epiandrosterone Epitestosterone HCG testosterone pregnenolone Dihydrotestosterone Isotope ratio mass spectrometry Methanol MeOH Carbon isotope ratios HCG, Human chorionic gonadotropin AND PREG high performance liquid chromatography HPLC cholesterol Doping control Human chorionic gonadotropin (hCG)