Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028224 | Steroids | 2010 | 6 Pages |
Abstract
Two new spirostanoides, filiasparosides E (1) and F (2), one new furostanoside, filiasparoside G (3), and one new ecdysterone, stachysterone A-20, 22-acetonide (4), together with six known steroidal saponins, asparagusin A (5), filiasparoside A (6), filiasparoside B (7), aspafilioside A (8), aspafilioside B (9), and filiasparoside C (10) were isolated from the roots of Asparagus filicinus Buch.-Ham. Their structures were elucidated on the basis of spectroscopic and chemical evidence. Compounds 1–10 were investigated for their cytotoxicities against human breast adenocarcinoma MDA-MB-231 cell line and compounds 8–10 exhibited cytotoxic activities with IC50 values ranging from 3.4 to 6.6 μM.
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Authors
Jia-Jun Wu, Ka-Wing Cheng, Xiao-Feng Zuo, Ming-Fu Wang, Ping Li, Lu-Yong Zhang, Hao Wang, Wen-Cai Ye,