Article ID Journal Published Year Pages File Type
2028241 Steroids 2012 6 Pages PDF
Abstract

We have developed a novel E-ring opening method for furostan, and applied it to prepare D-ring modified steroids, which can be used to synthesize cephalostatin analogs.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Development of a novel E-ring opening of furostan. ► Facile introduction of D-ring diene via transetherification. ► Stereoselective “Red-Ox” modification of steroidal D-ring diene.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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