Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028276 | Steroids | 2012 | 8 Pages |
Abstract
⺠In this study we showed the non-classical effect of testosterone, nandrolone and catechin in Sertoli cells. ⺠We investigated electrophysiological parameters in Sertoli cells and 45Ca2+ uptake. ⺠Catechin and nandrolone produced depolarization in the membrane of Sertoli cells and it was not affected by flutamide. ⺠The effects of nandrolone and catechin were blocked by diazoxide and U73122. ⺠We conclude that catechin and nandrolone act through the PLC-PIP2 pathway.
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Authors
Fernanda Carvalho Cavalari, Alexandre Luz de Castro, Bianca de Moraes Fracasso, EloÃsa da Silveira Loss,