| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2028303 | Steroids | 2011 | 6 Pages |
Abstract
An easy and fast procedure was developed for one-pot synthesis of steroidal isoxazoles starting from 23-acetylsapogenins derivatives in presence of P2O5/SiO2 in dry media under microwaves irradiation is described. Substrates of the 25S and 25R series were used as raw materials, establishing that this new methodology is applicable to both series.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Synthesis of new steroids bearing an isoxazole moiety in the side chain. ► One pot synthesis of 25R and 25S Steroidal isoxazoles. ► Fast synthesis of steroidal isoxazoles using MW in dry media.
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Biochemistry
Authors
María Guadalupe Hernández-Linares, Jesús Sandoval-Ramírez, Socorro Meza-Reyes, Sara Montiel-Smith, Gabriel Guerrero-Luna,