Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028337 | Steroids | 2012 | 8 Pages |
Abstract
⺠l-Thyroxine increases ROS production in THP-1 monocytes, through interaction with αvβ3 integrin. ⺠ROS production by thyroid hormones may induce cell migration and the effect is inhibited by the RGD peptide. ⺠Evidence from the literature points to a role of thyroid hormones in the activation of mammalian target of rapamycin (mTOR).
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Authors
Paolo De Vito, Valentina Balducci, Stefano Leone, Zulema Percario, Giorgio Mangino, Paul J. Davis, Faith B. Davis, Elisabetta Affabris, Paolo Luly, Jens Z. Pedersen, Sandra Incerpi,