Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028347 | Steroids | 2010 | 8 Pages |
Abstract
ⶠMicrobial transformation of dehydroepiandrosterone using Penicillium griseopurpureum Smith and Penicillium glabrum (Wehmer) Westling was reported for the first time. ⶠPenicillium griseopurpureum Smith yielded different monooxygenases to introduce hydroxyl groups at C-7α, 14α, and 15α positions of steroids. 15α-Hydroxy-17a-oxa-D-homo-4-androst-3, 17-dione was a novel metabolic product of DHEA transformed with P. griseopurpureum Smith. ⶠThe strain of P. glabrum (Wehmer) Westling catalyzed the DHEA to generate different D-lactones.
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Authors
Li-Hua Huang, Juan Li, Gong Xu, Xiang-Hua Zhang, Yang-Guang Wang, Ye-Lin Yin, Hong-Min Liu,