Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028359 | Steroids | 2010 | 9 Pages |
Abstract
â¶ Most cardenolides and bufadienolides inhibit the sodium pump non-selectively. â¶ A synthetic bufadienolide lacking the 14-OH inhibits the sodium pump selectively. â¶ Emicymarin is a weaker inhibitor of the leucocyte than the erythrocyte sodium pump. â¶ Selectivity may explain the symptomless pump inhibition seen in human hypertension.
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Authors
Philip J. Hilton, William McKinnon, Edward C. Gravett, Jean-Marie R. Peron, Christopher M. Frampton, M. Gary Nicholls, Gwyn Lord,