Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028513 | Steroids | 2011 | 10 Pages |
Abstract
⺠Three C27 bile acids [(24R,25R)-3α,7α,24-trihydroxy-5β-cholestan-27-oyl taurine as well as the (25R)- and (25S)-epimers of 3α,7α-dihydroxy-5β-cholestan-27-oyl taurine] were found to be major biliary bile acids in the capuchinbird (Perissocephalus tricolor) and bare-throated bellbird (Procnias nudicollis). ⺠Structures of these bile acids were established by HPLC, LC/ESI-MS/MS, and NMR as well as by a comparison of their chromatographic properties with those of synthetic reference standards. ⺠(24R,25R)-3α,7α,24-trihydroxy-5β-cholestan-27-oic acid has never been previously reported in any vertebrate species including mammals, although the presence of (24ξ,25ξ)-one with unidentified stereochemical configuration at C-24 and C-25 has been reported.
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Authors
Lee R. Hagey, Takashi Iida, Shoujiro Ogawa, Yuuki Adachi, Mizuho Une, Kumiko Mushiake, Masamitsu Maekawa, Miki Shimada, Nariyasu Mano, Alan F. Hofmann,