Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028543 | Steroids | 2011 | 6 Pages |
Abstract
⺠Aldosterone and angiotensin II signaling pathways crosstalk in vascular smooth muscle cells. ⺠Some genomic effects of angiotensin II are dependent on mineralocorticoid receptor transactivation. ⺠Some non-genomic effects of aldosterone are dependent on angiotensin type 1 receptor (AT1R) transactivation. ⺠Signaling crosstalk between angiotensin II and aldosterone-stimulated pathways contributes to the vascular pathophysiological effects of the renin-angiotensin-aldosterone system.
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Authors
Yohann Rautureau, Pierre Paradis, Ernesto L. Schiffrin,