| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2028578 | Steroids | 2009 | 5 Pages |
Abstract
Structural transformation of the steroidal lactone, oxandrolone (1), by suspended-cell cultures of the plant pathogen fungus Rhizopus stolonifer, resulted in the production of three new metabolites. These metabolites were identified as 11α-hydroxyoxandrolone (2), 6α-hydroxyoxandrolone (3) and 9α-hydroxyoxandrolone (4), by different spectroscopic methods and single-crystal X-ray diffraction analysis for metabolite 2. Compounds 1 and 3 showed a significant β-glucuronidase inhibitory activity.
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Authors
M. Iqbal Choudhary, Mohammad Yasin Mohammad, Syed Ghulam Musharraf, Masood Parvez, Amal Al-Aboudi, Atta-ur-Rahman,