| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2028644 | Steroids | 2009 | 4 Pages |
Abstract
Bioassay-guided purification of an ethanolic extract of Cystoseira myrica against HEPG-2 (liver) and HCT116 (colon) human cancer cell lines led to the isolation of 3-keto-22-epi-28-nor-cathasterone, 1 and cholest-4-ene-3,6-dione, 2. This finding allowed us to report for the first time that a brassinosteroid-related metabolite occurs in seaweed. These compounds showed activity in the range of 12.38–1.16 μM with selective activity of compound 2 to liver cancer cell lines.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Abdel-Hamid A. Hamdy, Elsayed A. Aboutabl, Somayah Sameer, Ahmed A. Hussein, Ana R. Díaz-Marrero, José Darias, Mercedes Cueto,