| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2028807 | Steroids | 2007 | 4 Pages |
Abstract
An effective deprotective method of spiro 3-cyclic thiaza ketal of steroidal 1,4-dien-3-ones using alkyl vinyl ether in the presence of protic acid followed by the treatment of aqueous alkali was described. This novel protocol could be fulfilled under mild condition with high yield. The mechanism mediated by a carbonium ion formed in situ was clarified by the capture of the cleaved fragment.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Bei Na Zhang, Ying Chen, Qian Zhang, Peng Xia,