Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028851 | Steroids | 2008 | 7 Pages |
Abstract
Preparative chemical methods for the synthesis of 10 degradation or photodecomposition products of mestranol and ethinyl estradiol (EE) are described. The synthesized compounds are useful as reference materials and standards for pharmaceutical analysis of mestranol and EE as bulk chemical or in formulated product. New synthetic methods were presented and the known synthetic procedures were improved. Detailed structural characterization of the degradation or photodecomposition products of mestranol and EE and related compounds was reported.
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Authors
Hongqi Li, Yanxi Song, Xianfu Peng,