Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028856 | Steroids | 2008 | 4 Pages |
Abstract
The preparation of ring-A fused steroidal dehydropiperazine at the 3,4-position is herein described. The novel steroidal dehydropiperazines were prepared from the annulation reaction of ethylenediamine with 3-keto-4-en steroids in a one-pot reaction under microwave irradiation. The key step involves base catalysed aerial oxidation of the C-6 methylene group followed by cyclocondensation of ethylenediamine via Michael addition reaction.
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Authors
Moyurima Borthakur, Madan G. Barthakur, Romesh C. Boruah,