Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2028961 | Steroids | 2007 | 4 Pages |
Abstract
The preparation of pyridine rings fused to the 3,4-positions of the steroid nucleus is herein described. These new pyridine derivatives were prepared in good yields by the reaction of propargylamine with 17β-hydroxyandrost-4-en-3-one, 17α-methyl-17β-hydroxyandrost-4-en-3-one, 17β-hydroxyestr-4-en-3-one catalyzed by Cu(II). The structure of 17β-hydroxy-5-ene-androst-3-eno[3,4-b]pyridine was determined by X-ray analysis.
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Authors
Ji-Zhong Yan, Jian Li, Guo-Wu Rao,