Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2029028 | Steroids | 2007 | 7 Pages |
Abstract
Microbial transformation of adrenosterone (1) by suspended-cell cultures of the filamentous fungus Cunninghamella elegans resulted in the production of five metabolites 2–6, which were identified as 9α-hydroxyadrenosterone (2), 11-ketotestosterone (3), 6β-hydroxyadrenosterone (4), 9α-hydroxy-11-ketotestosterone (5), and 6β-hydroxy-11-ketotestosterone (6). Structures of new metabolites 2, 5, and 6 were established by single-crystal X-ray diffraction analysis.
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Authors
Muhammad Iqbal Choudhary, Naik T. Khan, Syed G. Musharraf, Shazia Anjum, Atta-ur-Rahman,