| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2029030 | Steroids | 2007 | 10 Pages |
Abstract
A series of novel 1H- and 2H-indazole derivatives of the commercially available dehydroepiandrosterone acetate have been synthesized and tested for inhibition of human cytochrome 17α-hydroxylase-C17,20-lyase (CYP17), androgen receptor (AR) binding affinity, and cytotoxic potential against three prostate cancer (PC) cell lines.
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Authors
Vânia M.A. Moreira, Tadas S. Vasaitis, Vincent C.O. Njar, Jorge A.R. Salvador,