Solid-phase synthesis of libraries of ethynylated aminosteroid derivatives as potential antileukemic agents

Article ID	Journal	Published Year	Pages	File Type
2029135	Steroids	2016	10 Pages	PDF

Keywords

DMF PyBOP FMOC HOBt AcOH TFA PHE TLC PAL tetra-n-butylammonium fluoride THF TBAF DCM nuclear magnetic resonance 1-Hydroxybenzotriazole hydrate 6-chloro-1-hydroxybenzotriazole 9-fluorenylmethoxycarbonyl N,N-dimethylformamide N,N-diisopropylethylamine amino acid Steroid Trifluoroacetic acid Acetic acid Tetrahydrofuran NMR Room temperature Dichloromethane Hour Cancer Solid-phase synthesis Mass spectrometry Infrared spectroscopy Antiproliferative activity Phenylalanine DIPEA PRO Proline Linker HPLC high-performance liquid chromatography thin-layer chromatography

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

Solid-phase synthesis of libraries of ethynylated aminosteroid derivatives as potential antileukemic agents

Authors

Amélie Talbot, René Maltais, Lucie Carolle Kenmogne, Jenny Roy, Donald Poirier,