| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2029249 | Steroids | 2013 | 6 Pages |
Abstract
⺠Deproteinized bone mineral has specific anabolic potential in periosteal fibroblasts. ⺠Specific AR mediated actions in response to finasteride are validated by minocycline. ⺠AR mediated specificity is relevant to actions of deproteinized bone matrix in vitro. ⺠Results are interpreted in the context of androgen metabolites as markers of healing. ⺠Utilization of two androgen substrates validates similar responses to testing agents.
Keywords
hpfTNSALP17β-Hydroxysteroid dehydrogenaseGTR17β-HSDFBSDHTMMPGC-MS5α-DihydrotestosteroneROSALPTissue-nonspecific alkaline phosphataseAlkaline phosphataseGuided tissue regenerationminimum essential mediumfoetal bovine serumFinasteridematrixmetalloproteinaseMEMBone mineralMinocyclineHydroxyapatitegas chromatography/mass spectrometryReactive oxygen speciesAndrogen Receptor
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Authors
A. Suchak, M. Soory,